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  • ExperimentSetReplicate13
    • Dataset
  • Synthetic condensation assay of tudor domain13
    • Sample
    Treatments
    Assay Details
    Set Type
  • Replicate13
    • 16 Common Properties
     Project
    4DN
     Lab
    Karla Neugebauer, YALE
     Experiment Category
    Microscopy
     Experiment Type
    OptoDroplet
     Organism
    Mouse
     Sample Type
    immortalized cells
     Sample Tier
    Unclassified
     Sample Category
    Other
     Organ/System
    No value
     Tissue Source
    embryonic fibroblast
     Publication
    Courchaine EM et al. (2021) PMID:34115980
     Modifications
    No value
     Center
    TCPA - Neugebauer
     Status
    Released
     Commendations
    No value
     Warnings
    Biosample Metadata Incomplete
    Title
    Experiment Type
    Biosample
    Dataset
    Condition
    Assay Details
    Lab
    4DNESGSHWGUK
    OptoDroplet
    NIH3T3 expressing SMN tudor (Y130D) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (Y130D mutant)
    Target
    SMN1 engineered reagent protein with Y130D Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESRORWX8M
    OptoDroplet
    NIH3T3 expressing SMN tudor (Y109L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (Y109L mutant)
    Target
    SMN1 engineered reagent protein with Y109L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESGOUKUHY
    OptoDroplet
    NIH3T3 expressing SMN tudor (W102L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (W102L mutant)
    Target
    SMN1 engineered reagent protein with W102L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESQJS4P53
    OptoDroplet
    NIH3T3 expressing SMN tudor (E134K) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (E134K mutant)
    Target
    SMN1 engineered reagent protein with E134K Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESLBSY7UC
    OptoDroplet
    NIH3T3 expressing SMN tudor (F118L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (F118L mutant)
    Target
    SMN1 engineered reagent protein with F118L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESZZ8T7O9
    OptoDroplet
    NIH3T3 expressing SMNDC1 tudor Cry2
    Synthetic condensation assay of tudor domain
    Spf30 tudor domain
    Target
    SMNDC1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESMFGLQ3U
    OptoDroplet
    NIH3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, EPZ015666 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESM8F8PP5
    OptoDroplet
    NIH3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, MS023 + EPZ015666 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESI1DYYLS
    OptoDroplet
    NIH3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, MS023 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESPZNHYSY
    OptoDroplet
    NIH3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, mock treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNES9JHBEZC
    OptoDroplet
    NIH3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESVT8QSLU
    OptoDroplet
    NIH3T3 expressing Cry2 (negative control)
    Synthetic condensation assay of tudor domain
    mCherry-Cry2 negative control
    Target
    engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNES49WH1QD
    OptoDroplet
    NIH3T3 expressing hnRNPA1 IDR Cry2
    Synthetic condensation assay of tudor domain
    HNRNPA1 IDR
    Target
    HNRNPA1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    - fin -